Study shows personalized mRNA vaccine cuts melanoma recurrence risk in half after five years


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A Moderna experimental vaccine tailored to each patient's tumor cut odds of deadly skin cancer returning — and new five-year data shows the results holding.

CLEVELAND — Melanoma is the deadliest form of skin cancer. Even after surgery, about half of patients see the disease return within five years — a sobering reality that has driven researchers to look beyond standard treatment.

Now, a personalized mRNA vaccine combined with immunotherapy is showing results that could change that picture.

How the vaccine works

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